Trichloroacetic Acid is a CORROSIVE CHEMICAL and contact can severely irritate and burn the skin and eyes with possible eye damage.
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Common Name: TRICHLOROACETIC ACID CAS Number: 76-03-9 DOT Number: UN 1839 UN 2564 (Solution) ————————————————————————— HAZARD SUMMARY * Trichloroacetic Acid can affect you when breathed in. * Trichloroacetic Acid is a CORROSIVE CHEMICAL and contact can severely irritate and burn the skin and eyes with possible eye damage. * Breathing Trichloroacetic Acid can irritate the nose and throat. * Breathing Trichloroacetic Acid can irritate the lungs causing coughing and/or shortness of breath. Higher exposures can cause a build-up of fluid in the lungs (pulmonary edema), a medical emergency, with severe shortness of breath. * Trichloroacetic Acid may affect the liver. IDENTIFICATION Trichloroacetic Acid is a colorless, crystalline (sand-like) solid which is used in liquid solutions. It is used in making medicines, pharmaceuticals, and pesticides. REASON FOR CITATION * Trichloroacetic Acid is on the Hazardous Substance List because it is cited by ACGIH, DOT, NIOSH, IARC and IRIS. * This chemical is on the Sp ecial Health Hazard Substance List because it is CORROSIVE. * Definitions are provided on page 5. HOW TO DETERMINE IF YOU ARE BEING EXPOSED The New Jersey Right to Know Act requires most employers to label chemicals in the workplace and requires public employers to provide their employees with information and training concerning chemical hazards and controls. The federal OSHA Hazard Communi cation Standard, 1910.1200, requires private employers to provide similar training and information to their employees. * Exposure to hazardous substances should be routinely evaluated. This may include collecting personal and area air samples. You can obtain copies of sampling results from your employer. You have a legal right to this information under OSHA 1910.1020. RTK Substance number: 1883 Date: May 1997 Revision: May 2004 ————————————————————————— * If you think you are experiencing any work-related health problems, see a doctor trained to recognize occupational diseases. Take this Fact Sheet with you. WORKPLACE EXPOSURE LIMITS NIOSH: The recommended airborne exposure limit is 1 ppm averaged over a 10-hour workshift. ACGIH: The recommended airborne exposure limit is 1 ppm averaged over an 8-hour workshift. WAYS OF REDUCING EXPOSURE * Where possible, enclose operations and use local exhaust ventilation at the site of chemical release. If local exhaust ventilation or enclosure is not used, respirators should be worn. * Wear protective work clothing. * Wash thoroughly immediately after exposure to Trichloroacetic Acid and at the end of the workshift. * Post hazard and warning information in the work area. In addition, as part of an ongoing education and training effort, communicate all information on the health and safety hazards of Trichloroacetic Acid to potentially exposed workers.

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TRICHLOROACETIC ACID page 2 of 6 This Fact Sheet is a summary source of information of all potential and most severe health hazards that may result from exposure. Duration of exposure, concentration of the substance and other factors will affect your susceptibility to any of the potential effects described below. ————————————————————————— HEALTH HAZARD INFORMATION Acute Health Effects The following acute (short-term ) health effects may occur immediately or shortly after exposure to Trichloroacetic Acid : * Contact can severely irritate and burn the skin and eyes with possible eye damage. * Breathing Trichloroacetic Acid can irritate the nose and throat. * Breathing Trichloroacetic Acid can irritate the lungs causing coughing and/or shortness of breath. Higher exposures can cause a build-up of fluid in the lungs (pulmonary edema), a medical emergency, with severe shortness of breath. Chronic Health Effects The following chronic (long-term) health effects can occur at some time after exposure to Trichloroacetic Acid and can last for months or years: Cancer Hazard * While Trichloroacetic Acid has been tested, it is not classifiable as to its potential to cause cancer. Reproductive Hazard * There is limited evidence that Trichloroacetic Acid is a teratogen in animals. Until further testing has been done, it should be treated as a possible teratogen in humans. Other Long-Term Effects * Trichloroacetic Acid can irritate the lungs. Repeated exposure may cause bronchitis to develop with cough, phlegm, and/or shortness of breath. * Trichloroacetic Acid may affect the liver. MEDICAL Medical Testing If symptoms develop or overexposure is suspected, the following are recommended: * Chest x-ray and lung function tests. * Liver function tests. Any evaluation should include a careful history of past and present symptoms with an exam. Medical tests that look for damage already done are not a substitute for controlling exposure. Request copies of your medical testing. You have a legal right to this information under OSHA 1910.1020. Mixed Exposures * Because smoking can cause heart disease, as well as lung cancer, emphysema, and other respiratory problems, it may worsen respiratory conditions caused by chemical exposure. Even if you have smoked for a long time, stopping now will reduce your risk of developing health problems. * Because more than light al cohol consumption can cause liver damage, drinking alcohol may increase the liver damage caused by Trichloroacetic Acid . WORKPLACE CONTROLS AND PRACTICES Unless a less toxic chemical can be substituted for a hazardous substance, ENGINEERING CONTROLS are the most effective way of reducing exposure. The best protection is to enclose operations and/or provide local exhaust ventilation at the site of chemical release. Isolating operations can also reduce exposure. Using respirators or protective equipment is less effective than the controls mentioned above, but is sometimes necessary. In evaluating the controls presen t in your workplace, consider: (1) how hazardous the substance is, (2) how much of the substance is released into the workplace and (3) whether harmful skin or eye contact c ould occur. Special controls should be in place for highly toxic chemicals or when significant skin, eye, or breathing exposures are possible. In addition, the following control is recommended: * Where possible, automa tically transfer solid Trichloroacetic Acid or pump liquid Trichloroacetic Acid from drums or other storage containers to process containers. Good WORK PRACTICES can help to reduce hazardous exposures. The following work practices are recommended: * Workers whose clothing has been contaminated by Trichloroacetic Acid should change into clean clothing promptly. * Do not take contaminated work clothes home. Family members could be exposed. * Contaminated work clothes should be laundered by individuals who have been informed of the hazards of exposure to Trichloroacetic Acid . * Eye wash fountains should be provided in the immediate work area for emergency use. * If there is the possibility of skin exposure, emergency shower facilities should be provided. * On skin contact with Trichloroacetic Acid , immediately wash or shower to remove the chemical. At the end of the workshift, wash any areas of the body that may have contacted Trichloroacetic Acid , whether or not known skin contact has occurred.

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TRICHLOROACETIC ACID page 3 of 6 * Do not eat, smoke, or drink where Trichloroacetic Acid is handled, processed, or stored , since the chemical can be swallowed. Wash hands carefully before eating, drinking, smoking, or using the toilet. * For solid Trichloroacetic Acid use a vacuum or a wet method to reduce dust during clean-up. DO NOT DRY SWEEP. PERSONAL PROTECTIVE EQUIPMENT WORKPLACE CONTROLS ARE BETTER THAN PERSONAL PROTECTIVE EQUIPMENT. However, for some jobs (such as outside work, confined space entry, jobs done only once in a while, or jobs done while workplace controls are being installed), personal protective equipment may be appropriate. OSHA 1910.132 requires employers to determine the appropriate personal protective equipment for each hazard and to train employees on how and when to use protective equipment. The following recommendations are only guidelines and may not apply to every situation. Clothing * Avoid skin contact with Trichloroacetic Acid . Wear acid- resistant gloves and clothing. Safety equipment suppliers/manufacturers can provide recommendations on the most protective glove/clothing material for your operation. * All protective clothing (suits, gloves, footwear, headgear) should be clean, available each day, and put on before work. * Safety equipment manufacturers recommend Viton as a protective material. Eye Protection * For solid Trichloroacetic Acid , wear eye protection with side shields or goggles. * Wear indirect-vent, impact and splash resistant goggles when working with liquids. * Wear a face shield along with goggles when working with corrosive, highly irritating or toxic substances. * Contact lenses should not be worn when working with this substance. Respiratory Protection IMPROPER USE OF RESPIRATORS IS DANGEROUS. Such equipment should only be used if the employer has a written program that takes into account workplace conditions, requirements for worker training, respirator fit testing and medical exams, as described in OSHA 1910.134. * Where the potential exists for exposure over 1 ppm, use a NIOSH approved full facepiece respirator with high efficiency particulate prefilters and an acid gas cartridge/canister. Greater protection is provided by a powered-air purifying respirator. Particulate filters must be checked every day before work for physical damage, such as rips or tears, and replaced as needed. * If while wearing a filter or cartridge respirator you can smell, taste, or otherwise detect Trichloroacetic Acid , or if while wearing particulate filters abnormal resistance to breathing is experienced, or eye irritation occurs while wearing a full facepiece respirator, leave the area immediately. Check to make su re the respirator-to-face seal is still good. If it is, replace the filter or cartridge. If the seal is no longer good, you may need a new respirator. * Be sure to consider all potential exposures in your workplace. You may need a combination of filters, prefilters or cartridges to protect against different forms of a chemical (such as vapor and mist) or against a mixture of chemicals. * Where the potential for high exposure exists, use a MSHA/NIOSH approved supplied-air respirator with a full facepiece operated in a pressure-demand or other positive- pressure mode. For increased protection use in combination with an auxiliary self-contained breathing apparatus operated in a pressure-demand or other positive-pressure mode. QUESTIONS AND ANSWERS Q: If I have acute health effects, will I later get chronic health effects? A: Not always. Most chronic (long-term) effects result from repeated exposures to a chemical. Q: Can I get long-term effects without ever having short- term effects? A: Yes, because long-term e ffects can occur from repeated exposures to a chemical at levels not high enough to make you immediately sick. Q: What are my chances of getting sick when I have been exposed to chemicals? A: The likelihood of becoming sick from chemicals is increased as the amount of exposure increases. This is determined by the length of time and the amount of material to which someone is exposed. Q: When are higher exposures more likely? A: Conditions which increase risk of exposure include dust releasing operations (grinding, mixing, blasting, dumping, etc.), other physical and mech anical processes (heating, pouring, spraying, spills and evaporation from large surface areas such as open containers), and “confined space” exposures (working insi de vats, reactors, boilers, small rooms, etc.). Q: Is the risk of getting sick higher for workers than for community residents? A: Yes. Exposures in the community, except possibly in cases of fires or spills, are usually much lower than those found in the workplace. However, people in the community may be exposed to contaminated water as well as to chemicals in the air over long periods. This may be a problem for children or people who are already ill.

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TRICHLOROACETIC ACID page 4 of 6 Q: Can men as well as women be affected by chemicals that cause reproductive system damage? A: Yes. Some chemicals reduce potency or fertility in both men and women. Some damage sperm and eggs, possibly leading to birth defects. Q: Who is at the greatest risk from reproductive hazards? A: Pregnant women are at great est risk from chemicals that harm the developing fetus. However, chemicals may affect the ability to have children, so both men and women of childbearing age are at high risk. Q: Should I be concerned if a chemical is a teratogen in animals? A: Yes. Although some chemicals may affect humans differently than they affect animals, damage to animals suggests that similar damage can occur in humans. ————————————————————————– The following information is available from: New Jersey Department of Health and Senior Services Occupational Health Service PO Box 360 Trenton, NJ 08625-0360 (609) 984-1863 (609) 984-7407 (fax) Web address: Industrial Hygiene Information Industrial hygienists are available to answer your questions regarding the control of chemical exposures using exhaust ventilation, special work practices, good housekeeping, good hygiene practices, and personal protective equipment including respirators. In addition, they can help to interpret the results of industrial hygiene survey data. Medical Evaluation If you think you are becoming si ck because of exposure to chemicals at your workplace, you may call personnel at the Department of Health and Se nior Services, Occupational Health Service, who can help you find the information you need. Public Presentations Presentations and educational programs on occupational health or the Right to Know Act can be organized for labor unions, trade associations and other groups. Right to Know Information Resources The Right to Know Infoline (609) 984-2202 can answer questions about the identity a nd potential health effects of chemicals, list of educational materials in occupational health, references used to prepare the Fact Sheets, preparation of the Right to Know Survey, education and training programs, labeling requirements, and gene ral information regarding the Right to Know Act. Violations of the law should be reported to (609) 984-2202. ————————————————————————–

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TRICHLOROACETIC ACID page 5 of 6 DEFINITIONS ACGIH is the American Conference of Governmental Industrial Hygienists. It recommends upper limits (called TLVs) for exposure to workplace chemicals. A carcinogen is a substance that causes cancer. The CAS number is assigned by the Chemical Abstracts Service to identify a specific chemical. CFR is the Code of Federal Regulations, which consists of the regulations of the United States government. A combustible substance is a solid, liquid or gas that will burn. A corrosive substance is a gas, liquid or solid that causes irreversible damage to human tissue or containers. DEP is the New Jersey Department of Environmental Protection. DOT is the Department of Transportation, the federal agency that regulates the transportation of chemicals. EPA is the Environmental Protection Agency, the federal agency responsible for regulating environmental hazards. A fetus is an unborn human or animal. A flammable substance is a solid, liquid, vapor or gas that will ignite easily and burn rapidly. The flash point is the temperature at which a liquid or solid gives off vapor that can form a flammable mixture with air. IARC is the International Agency for Research on Cancer, a scientific group that classifies chemicals according to their cancer-causing potential. IRIS is the Integrated Risk Information System database of the federal EPA. A miscible substance is a liquid or gas that will evenly dissolve in another. mg/m3 means milligrams of a chemical in a cubic meter of air. It is a measure of concentration (weight/volume). A mutagen is a substance that causes mutations. A mutation is a change in the genetic material in a body cell. Mutations can lead to birth defects, miscarriages, or cancer. NAERG is the North American Emergency Response Guidebook. It was jointly developed by Transport Canada, the United States Department of Transportation and the Secretariat of Communications and Transportation of Mexico. It is a guide for first responders to quickly identify the specific or generic hazards of material involved in a transportation incident, and to protect themselves and the general public during the initial response phase of the incident. NFPA is the National Fire Protection Association. It classifies substances according to their fire and explosion hazard. NIOSH is the National Institute for Occupational Safety and Health. It tests equipment, evaluates and approves respirators, conducts studies of workplace h azards, and proposes standards to OSHA. NTP is the National Toxicology Program which tests chemicals and reviews evidence for cancer. OSHA is the Occupational Safety and Health Administration, which adopts and enforces health and safety standards. PEL is the Permissible Exposure Limit which is enforceable by the Occupational Safety and Health Administration. PIH is a DOT designation for chemicals which are Poison Inhalation Hazards. ppm means parts of a substance per million parts of air. It is a measure of concentration by volume in air. A reactive substance is a solid, liquid or gas that releases energy under certain conditions. STEL is a Short Term Exposure Limit which is usually a 15- minute exposure that should not be exceeded at any time during a work day. A teratogen is a substance that causes birth defects by damaging the fetus. TLV is the Threshold Limit Value, the workplace exposure limit recommended by ACGIH. The vapor pressure is a measure of how readily a liquid or a solid mixes with air at its surface. A higher vapor pressure indicates a higher concentration of the substance in air and therefore increases the likelihood of breathing it in.

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page 6 of 6 >>>>>>>>>>>>>>>>> E M E R G E N C Y I N F O R M A T I O N <<<<<<<<<<<<<<<<< Common Name: TRICHLOROACETIC ACID DOT Number: UN 1839 UN 2564 (Solution) NAERG Code: 153 CAS Number: 76-03-9 Hazard rating NJDHSS NFPA FLAMMABILITY 0 - REACTIVITY 0 - CORROSIVE POISONOUS GASES ARE PRODUCED IN FIRE CONTAINERS MAY EXPLODE IN FIRE Hazard Rating Key: 0=minimal; 1=slight; 2=moderate; 3=serious; 4=severe FIRE HAZARDS * Trichloroacetic Acid may burn, but does not readily ignite. * Use dry chemical, CO 2, alcohol or polymer foam extinguishers. * POISONOUS GASES ARE PRODUCED IN FIRE, including Chloroform, Phosgene and Hydrogen Chloride . * CONTAINERS MAY EXPLODE IN FIRE. * Use water spray to keep fire-exposed containers cool. * If employees are expected to fight fires, they must be trained and equipped as stated in OSHA 1910.156. SPILLS AND EMERGENCIES If Trichloroacetic Acid is spilled or leaked, take the following steps: * Evacuate persons not wearing protective equipment from area of spill or leak until clean-up is complete. * Cover with dry lime, sand or soda ash and place in covered containers for disposal. * Ventilate and wash area after clean-up is complete. * It may be necessary to contain and dispose of Trichloroacetic Acid as a HAZARDOUS WASTE. Contact your state Department of Environmental Protection (DEP) or your regional office of the federal Environmental Protection Agency (EPA) for specific recommendations. * If employees are required to clean-up spills, they must be properly trained and equipped. OSHA 1910.120(q) may be applicable. =============== FOR LARGE SPILLS AND FIRES immediately call your fire department. You can request emergency information from the following: CHEMTREC: (800) 424-9300 NJDEP HOTLINE: 1-877-WARN-DEP =============== HANDLING AND STORAGE * Prior to working with Trichloroacetic Acid you should be trained on its proper handling and storage. * A violent reaction may occur when Trichloroacetic Acid is mixed with COPPER in DIMETHYL SULFOXIDE. * Trichloroacetic Acid is not compatible with OXIDIZING AGENTS (such as PERCHLORATES, PEROXIDES, PERMANGANATES, CHLORATES, NITRATES, CHLORINE, BROMINE and FLUORINE); and STRONG BASES (such as SODIUM HYDROXIDE and POTASSIUM HYDROXIDE). * Store in tightly closed containers in a cool, well-ventilated area away from METALS and MOISTURE. FIRST AID For POISON INFORMATION call 1-800-222-1222 Eye Contact * Immediately flush with large amounts of water. Continue without stopping for at leas t 30 minutes, occasionally lifting upper and lower lids. Seek medical attention immediately. Skin Contact * Quickly remove contaminated clothing. Immediately wash area with large amounts of soap and water. Seek medical attention immediately. Breathing * Remove the person from exposure. * Begin rescue breathing (usi ng universal precautions) if breathing has stopped and CPR if heart action has stopped. * Transfer promptly to a medical facility. * Medical observation is recommended for 24 to 48 hours after breathing overexposure, as pulmonary edema may be delayed. PHYSICAL DATA Flash Point: greater than 230oF (110oC) Water Solubility: Soluble OTHER COMMONLY USED NAMES Chemical Name: Acetic Acid, Trichloro- -------------------------------------------------------------------------- Not intended to be copied and sold for commercial purposes. -------------------------------------------------------------------------- NEW JERSEY DEPARTMENT OF HEALTH AND SENIOR SERVICES Right to Know Program PO Box 368, Trenton, NJ 08625-0368 (609) 984-2202 -------------------------------------------------------------------------- 163 KB – 6 Pages